Piperaziniocephalosporins
US5143910A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 23, 1990 |
| Grant date | Sep 1, 1992 |
| Priority date | — |
| Expiry date | Aug 23, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D505/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Antibacterial hydroxyarylpiperazinocephalosporins of the formula: ##STR1## wherein R.sup.1 is amino or acylamino; R.sup.2 is H or methoxy; R.sup.3 is alkyl; R.sup.4 is --(P--C--Q).sub.n --, where P and Q each are H, alkyl or OH, or P and Q combine to form oxo, and n is 0 or 4; R.sup.5 is substituted or unsubstituted hydroxyaryl; R.sup.6 has a negative charge and is COO, or an anion in combination with an optionally protected carboxy; and X is O, S or S.fwdarw.O; an antibacterial preparation containing the same; a method for killing bacteria and preventing or treating bacterial infection by using the same; and syntheses of the cephalosporins are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.