Oxodihydropyridyl chroman derivatives

US5143924A · kind A · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Rolf Gericke · Seeheim-Jugenheim, DE
• Manfred Baumgarth
• Ingeborg Lues · Darmstadt, DE
• Rolf Bergmann
• Jacques De Peyer · Darmstadt, DE

Key dates

• Filing date: Jul 23, 1990
• Grant date: Sep 1, 1992
• Expiry date: Jul 23, 2010

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D405/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Novel chroman derivatives of the formula I ##STR1## in which R.sup.1 to R.sup.6 and Z have the meanings given in Patent Claim 1, and their salts show effects on the cardiovascular system and can be used for the treatment or prophylaxis of cardiac insufficiency, angina pectoris, high blood pressure, incontinence and alopecia.