Substituted pyridine-2,4-dicarboxylic acid compounds and methods of use thereof

US5143926A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Ekkehard Baader · Königstein, DE
• Martin Bickel · Frankfurt am Main, DE
• Dietrich Brocks · Wiesbaden, DE
• Volkmar Gunzler · Marburg, DE
• Stephan Henke · Bad Soden am Taunus, DE
• Hartmut Hanauske-Abel · Edgewater, US

Key dates

• Filing date: Oct 31, 1990
• Grant date: Sep 1, 1992
• Expiry date: Oct 31, 2010

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D213/81
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to substituted pyridine-2,4-dicarboxylic acid derivatives of the formula I ##STR1## in which R.sup.1 and R.sup.2 have the meanings given. The invention also relates to a process for the preparation of the abovementioned compounds and to their use as medicaments, in particular as fibrosuppressants and immunosuppressants.