Conjugates in which a monovalent carboxylic ionophore is associated by means of a covalent bond with a macromolecule, their use as immunotoxin potentiators and the intermediate activated inophores
US5144009A · kind A · utility
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2References
17Claims
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Inventors
Key dates
| Filing date | Dec 28, 1989 |
| Grant date | Sep 1, 1992 |
| Priority date | — |
| Expiry date | Dec 28, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/01
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to conjugates in which a monovalent carboxylic ionophore is associated by means of a covalent bond with a macromolecule chosen from antibodies, fragments of antibodies, proteins such as peptide hormones or human proteins, and peptide ligands. It also relates to the activated inophores. These conjugates are suitable as immunotoxin potentiators.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.