Cytotoxic drug conjugates
US5144012A · kind A · utility
21Cited by
2References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 15, 1991 |
| Grant date | Sep 1, 1992 |
| Priority date | — |
| Expiry date | Feb 15, 2011 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/807
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Conjugates of antibodies and cytotoxic methotrexate drugs make use of liners between the drug and antibody which are simple organic groups, wherein the link to the antibody is an acyl group and the link to the drug is an alkylidene hydrazide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.