Process for preparation of dipeptides
US5144073A · kind A · utility
38Cited by
4References
8Claims
0Family size
Inventor
Key dates
| Filing date | Sep 14, 1989 |
| Grant date | Sep 1, 1992 |
| Priority date | — |
| Expiry date | Sep 14, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/0613
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed is a process for synthesis of a dipeptide such as N-acetyl-L-.alpha.-aspartyl-L-phenylalanine methyl ester wherein one amino acid serves as a chiral template which allows for synthesis of a second amino acid residue to form said dipeptide. The process involves several novel steps such as a nucleophile addition step. In addition, several novel intermediates are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.