Surface modified drug nanoparticles
US5145684A · kind A · utility
979Cited by
5References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 25, 1991 |
| Grant date | Sep 8, 1992 |
| Priority date | — |
| Expiry date | Jan 25, 2011 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y5/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Dispersible particles consisting essentially of a crystalline drug substance having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 400 nm, methods for the preparation of such particles and dispersions containing the particles. Pharmaceutical compositions containing the particles exhibit unexpected bioavailability and are useful in methods of treating mammals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.