Bactericidal formulations for use in veterinary medicine

US5145853A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Karl G. Metzger · Wuppertal, DE
• Hans-Joachim Zeiler · Velbert, DE
• Martin Scheer · Wuppertal, DE
• Herbert Voege · Leverkusen, DE
• Klaus Grohe · Odenthal, DE

Key dates

• Filing date: Jan 2, 1991
• Grant date: Sep 8, 1992
• Expiry date: Jan 2, 2011

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A40/70
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method of treating livestock infected with, or protecting livestock against infection from, bacteria which comprises administering to such livestock an antibacterially effective amount of a quinolonecarboxylic acid or derivative of the formula ##STR1## in which A represents nitrogen or .dbd.C--R.sup.4, PA0 R.sup.4 represents hydrogen, fluorine, chlorine, nitro or methyl, PA0 B represents ##STR2## and B also represents ##STR3## when R.sup.1 does not denote cyclopropyl, and R.sup.5 represents hydrogen, a branched or unbranched alkyl group which has 1 to 4 carbon atoms and which can optionally be substituted by a hydroxyl or methoxy group, PA1 R.sup.6 represents hydrogen, methyl or phenyl, PA1 R.sup.7 represents hydrogen or methyl, PA1 R.sup.8 represents amino, alkyl- or dialkylamino having 1 or 2 carbon atoms in the alkyl group, aminomethyl, alkyl- or dialkylaminomethyl having 1 or 2 carbon atoms in the alkyl group, PA0 R.sup.1 represents an alkyl radical having 1 to 3 carbon atoms, cyclopropyl, 2-fluoroethyl vinyl, methoxy, 4-fluorophenyl or methylamino, PA0 R.sup.2 represents hydrogen, alkyl having 1 to 6 carbon atoms, and cyclohexyl, benzyl, 2-oxopropyl, phenacyl and ethoxycarbo…