Pyrrolo [1,2-a] imidazole and imidazo [1,2a] pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors

US5145858A · kind A · utility

Assignee

• SmithKline Beecham Limited · US

Inventors

• Jerry L. Adams · Wayne, US
• Paul E. Bender · Cherry Hill, US
• John G. Gleason · Downingtown, US
• Nabil Hanna · Olivenhain, US
• John F. Newton · West Chester, US
• Carl D. Perchonock · Philadelphia, US

Key dates

• Filing date: Dec 26, 1991
• Grant date: Sep 8, 1992
• Expiry date: Dec 26, 2011

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F7/2208
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds comprising pyridyl and phenyl substituted pyrrolo[1,2-a]imidazole derivatives and pyridyl and phenyl substituted imidazo[1,2-a]pyridine derivatives, pharmaceutical compositions containing said compounds, and their use as 5-lipoxygenase pathway inhibitors.