Process for the preparation of anti-hypertensive benzopyran derivative
US5145985A · kind A · utility
5Cited by
4References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 25, 1990 |
| Grant date | Sep 8, 1992 |
| Priority date | — |
| Expiry date | Jun 25, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D311/58
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process is disclosed for the preparation of (.+-.)-6-cyano-3,4-dihydro-2,2-dimethyl-trans-4-(2-oxo-1-pyrrol idino)-2H-1-benzopyran-3-ol of the Formula (VI) ##STR1## from 4-cyanophenol of the Formula (I) ##STR2## which comprises reacting 4-cyanophenol of the Formula (I) with isoprene, followed with bromination and dehydrobromination steps with formation of intermediates to react with 2-pyrrolidone resulting in obtaining the compound of the Formula (VI).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.