Production of dispersions of spherical particles by crystallization of emulsions

US5147412A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Bernd Klinksiek · Bensberg, DE
• Dietmar Kalz · Neunkirchen, DE
• Carsten Gerdes · Leverkusen, DE
• Ferdinand Kummeler · Leverkusen, DE
• Gunter Heinrich · Leverkusen, DE
• Karl Reizlein · Cologne, DE
• Manfred Zimmermann · Monheim, DE

Key dates

• Filing date: Dec 2, 1991
• Grant date: Sep 15, 1992
• Expiry date: Dec 2, 2011

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01F23/482
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

The invention relates to a process in which a melt is mixed with, and emulsified in a colder aqueous phase at a temperature below the crystallization point of the molten compound, the melt only solidifying in the form of the dispersed particles after the emulsification step. To this end, the melt is sprayed into the aqueous phase to form a preliminary emulsion (12) and the preliminary emulsion is finely dispersed for 0.005 s to 0.15 s in a following homogenization nozzle (8) to form an emulsion (15) which then solidifies to form the final crystal suspension. The particle size can be clearly and reproducibly adjusted through the nozzle pressure during the emulsification step. The process may be used in particular for the production of highly concentrated dispersions of high-melting organic materials.