Process for cross-linking collagenous material and resulting product
US5147514A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jul 30, 1990 |
| Grant date | Sep 15, 1992 |
| Priority date | — |
| Expiry date | Jul 30, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08H1/06
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention relates to a process for cross-linking a proteinaceous material. The process comprises: i) soaking the material to be cross-linked in an aqueous solution of high osmolality; ii) incubating the material in an aqueous buffer including an amount of a photooxidative catalyst sufficient to catalyze photooxidation of the material; and iii) irradiating the material and the catalyst of step (i) with light that includes a range of wavelengths selectively absorbed by the catalyst. Irradiation is effected under conditions such that cross-linking of the material occurs. In a further embodiment, the present invention relates to a cross-linked product produced by the above-described method.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.