Method of inhibiting the influx of leukocytes into organs during sepsis or other trauma
US5147637A · kind A · utility
36Cited by
4References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 31, 1989 |
| Grant date | Sep 15, 1992 |
| Priority date | — |
| Expiry date | Mar 31, 2009 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The influx of leukocytes into the lung and other organs during sepsis or other infectious or non-infectious trauma can be inhibited by the administration of anti-CD18 monoclonal antibodies. Such inhibition results in a prevention and/or diminishment of organ damage in inflammations and especially in endotoxic shock and adult respiratory distress syndrome.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.