Thrombin composition for oral administration
US5149540A · kind A · utility
72Cited by
9References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 27, 1991 |
| Grant date | Sep 22, 1992 |
| Priority date | — |
| Expiry date | Feb 27, 2011 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P7/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A stable thrombin composition for oral administration having an excellent solubility is prepared with thrombin as a hemostatic ingredient, gelatin, albumin and glycine as a stabilizer and sucrose and/or sugar alcohol as a carrier. The thrombin composition is effective for the treatment of hemorrhage in the upper alimentary canal, is stable even at room temperature conditions for long periods of time, has excellent solubility and can be orally administered in a simple manner.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.