Method of inhibiting progenitor cell proliferation
US5149544A · kind A · utility
24Cited by
6References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 13, 1989 |
| Grant date | Sep 22, 1992 |
| Priority date | — |
| Expiry date | Nov 13, 2009 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/838
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention comprises a factor having the following characteristics: PA0 a) It inhibits granulocyte-macrophage colony and cluster formation; PA0 b) It has a molecular weight of about 8 kDa as determined by SDS-PAGE; PA0 c) It has a weak anionic charge at pH 7.4 as shown by anion exchange chromatography; PA0 d) It has a flattened isoelectric titration curve as shown by anion exchange chromatography; and PA0 e) It is a protein. The invention also comprises methods of making and using the factor and compositions comprising the factor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.