Human insulin analogs and preparations containing them
US5149777A · kind A · utility
40Cited by
0References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 19, 1991 |
| Grant date | Sep 22, 1992 |
| Priority date | — |
| Expiry date | Mar 19, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel human insulin analogs exhibiting high biological activity and in which the amino acid residue Phe.sup.B25 is substituted by His or Tyr and moreover substitutions may optionally be present in one or more of the positions A4, A8, A17, A21, B9, B10, B12, B13, B21, B26, B27, B28, and B30, as well as the amino acid residue in the B30 position may further be totally missing or may be blocked at the C-terminal in the form of ester or amide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.