Cyclic peptides for treating herpes infections
US5149778A · kind A · utility
5Cited by
1References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 3, 1990 |
| Grant date | Sep 22, 1992 |
| Priority date | — |
| Expiry date | Jul 3, 2010 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/27
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are cyclic peptide derivatives of the formula ##STR1## wherein A is absent or the tripeptide radical Thr.rarw.Gly.rarw.Ala, R.sup.1 is benzyl or benzyl monosubstituted at position 4 of the aromatic ring with halo, hydroxy, lower alkyl or lower alkoxy, R.sup.2 and R.sup.4 each independently is hydrogen or lower alkyl, R.sup.3 is lower alkyl or lower alkyl monosubstituted with a hydroxy, R.sup.5 is lower alkyl, Y is oxo or thioxo and Z is hydroxy or NR.sup.6 R.sup.7 wherein R.sup.6 and R.sup.7 each independently is hydrogen or lower alkyl. The derivatives are useful for treating herpes infections.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.