Process for the preparation of omega-arylalkanoic acids
US5149866A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 14, 1991 |
| Grant date | Sep 22, 1992 |
| Priority date | — |
| Expiry date | Aug 14, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C59/52
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present inventon pertains to a process for the preparation of omega-arylalkanoic acids of the genral formula EQU R--Ar--R.sup.1 --COOH wherein R is hydrogen, hydroxy, C.sub.1 -C.sub.8 alkyl, C.sub.1 -C.sub.8 alkoxy, or aryl; wherein R.sup.1 is C.sub.1 -C.sub.4 alkyl; and wherein Ar is an aryl group which can be further substituted with at least one of hydroxy, C.sub.1 -C.sub.8 alkyl, C.sub.1 -C.sub.8 alkoxy, aryl, halide, amino, or acetamido. The omega arylalkanoic acids of the given formula are prepared using catalysts which provide an improvement over the known Willgerodt-Kindler reaction. The present invention also pertains to methods for removing sulfur during the above-described process for the preparation of the omega-arylalkanoic acids.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.