Polysulfides compounds and lipid peroxidation inhibitor containing the polysulfide compounds as active ingredient
US5149879A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 21, 1991 |
| Grant date | Sep 22, 1992 |
| Priority date | — |
| Expiry date | Jun 21, 2011 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P39/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A lipid peroxidation inhibitor contains a polysulfide compound represented by formula (I) as an active ingredient: EQU R.sup.1 --(S).sub.m --R.sup.2 (I) wherein R.sup.1 and R.sup.2 are same or different hydrocarbon chains having 1 to 16 carbon atoms and m is an integer of 3 to 10. Among compounds (I) are found novel which are: EQU R.sup.3 --(S).sub.n --R.sup.4 (II) wherein R.sup.3 and R.sup.4 are same or different lower alkenyl groups and n is an integer of 6 to 10. Pharmaceutical compositions which contain a polysulfide compound represented by formula (I) as an active ingredient, for preventing and curing diseases of thrombosis, arteiosclerosis, liver troubles, pulmonary edema, skin troubles, eye troubles and aging are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.