Patent · US Expired

Intermediates in the preparation of chiral spirofluorenehydantoins

US5151544A · kind A · utility

1Cited by
10References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 25, 1990
Grant dateSep 29, 1992
Priority date
Expiry dateMay 25, 2010

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2603/18
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Disclosed is a process for the synthesis of enantiomerically pure R and S isomers of 2,7-difluoro-4-methoxyspiro[9H-fluorene-9,4-imidazolidene]-2',5'-dione from 2,7-difluoro-4-methoxyfluorenone. Intermediate amino acid esters and urea esters and their preparation are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.