Patent · US Expired

Method for culturing mammalian cells in a horizontally rotated bioreactor

US5153133A · kind A · utility

39Cited by
13References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 15, 1991
Grant dateOct 6, 1992
Priority date
Expiry dateApr 15, 2011

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/818
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A bio-reactor system where cell growth microcarrier beads are suspended in a zero head space fluid medium by rotation about a horizontal axis and where the fluid is continuously oxygenated from a tubular membrane which rotates on a shaft together with rotation of the culture vessel. The oxygen is continuously throughput through the membrane and disbursed into the fluid medium along the length of the membrane.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.