Pyridine-2,4- and -2,5-dicarboxylic acid amides and their medicinal compositions and methods of use

US5153208A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Martin Bickel · Frankfurt am Main, DE
• Dietrich Brocks · Wiesbaden, DE
• Harald Burghard · Schmitten, DE
• Volkmar Gunzler · Marburg, DE
• Stephan Henke · Bad Soden am Taunus, DE
• Hartmut Hanauske-Abel · Edgewater, US
• Jurgen Mohr · Grünstadt, DE
• Georg Tschank · Frankfurt am Main, DE

Key dates

• Filing date: Jul 1, 1991
• Grant date: Oct 6, 1992
• Expiry date: Jul 1, 2011

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to pyridine-2,4- and -2,5-dicarboxylic acid derivatives of the formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4 and X have the meanings given, a process for the preparation of these compounds and their use, in particular in medicaments for influencing the metabolism of collagen and collagen-like substances or the biosynthesis of Cl.sub.q.