9-amino-2-phenylbicyclo[3.3.1]nonanes and 9-amino-2-phenylbicyclo[3.3.1]non-2-enes and drugs containing them

US5153228A · kind A · utility

Assignee

• BASF SE

Inventors

• Rainer Schlecker · Bissersheim, DE
• Hans P. Hofmann · Schifferstadt, DE
• Laszlo Szabo · Ditzingen, DE

Key dates

• Filing date: Jun 11, 1991
• Grant date: Oct 6, 1992
• Expiry date: Jun 11, 2011

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2602/46
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

9-Amino-2-phenylbicyclo-[3.3.1]nonanes and 9-amino-2-phenylbicyclo[3.3.1]non-2-enes of the formula I ##STR1## where R.sup.1 and R.sup.2 are identical or different and each is hydrogen, halogen, alkyl, alkoxy, dialkylamino, trifluoromethyl, hydroxyl, alkylthio, alkylsulfonyl or nitro, R.sup.3 and R.sup.4 are identical or different and each is hydrogen, alkyl or 1 to 5 or alkenyl or alkynyl of 2 to 5 carbon atoms, or benzyl, it also being possible for R.sup.3 and R.sup.4 together to form a saturated chain which contains from three to seven carbon atoms and can be substituted by phenyl, and where is a single or double bond, are used for producing drugs which act, in particular, on the central nervous system.