Phosphonate, phosphinate derivatives useful as antihypertensive agents
US5153347A · kind A · utility
25Cited by
10References
5Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jan 31, 1991 |
| Grant date | Oct 6, 1992 |
| Priority date | — |
| Expiry date | Jan 31, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/4075
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel angiotensin II receptor antagonists of the formula ##STR1## wherein X, X.sub.1, X.sub.2, R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are as defined herein, are disclosed. These compounds are useful, for example, in the treatment of hypertension, congestive heart failure and cardiac hypertrophy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.