Nucleic acids labeled with a chemiluminescent acridine ester
US5155216A · kind A · utility
3Cited by
11References
11Claims
0Family size
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Key dates
| Filing date | Apr 8, 1991 |
| Grant date | Oct 13, 1992 |
| Priority date | — |
| Expiry date | Apr 8, 2011 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/533
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Polynucleotides are labeled with chemiluminescent acridine esters or luminescent lanthanides. Labelling is preferably carried out by incorporating a functional group into a nucleotide or polynucleotide at the C4 position of the pyrimidine portion or the C6 position of the purine portion and bonding a chemiluminescent acridine ester or a luminescent lanthanide to the functional group. The labeled polynucleotides are useful for direct detection of homologous polynucleotide sequences.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.