Preparation of quinolinecarboxylic acids

US5155223A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventor

• Michael Preiss · Leinfelden, DE

Key dates

• Filing date: Jun 3, 1991
• Grant date: Oct 13, 1992
• Expiry date: Jun 3, 2011

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D215/56
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

##STR1## is reacted with an amine ##STR2## to give the compound of the formula ##STR3## Because the starting material (I) has F in 7-position rather than Cl, the reaction proceeds at relatively low temperature with minimum side reactions.