Aldose reductase inhibitor
US5155259A · kind A · utility
19Cited by
0References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 8, 1991 |
| Grant date | Oct 13, 1992 |
| Priority date | — |
| Expiry date | Aug 8, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C59/64
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An aldose reductase inhibitor, comprising a compound of the formula (I) ##STR1## or a pharmaceutically acceptable salt thereof as the effective component, in which R is lower alkyl or cyclohexylmethyl and n is 2 or 3. The compounds of formula (I) and salts thereof according to the invention exhibit a superior aldose reductase inhibiting activity with simultaneous high stability, so that they are useful for the prevention and therapy of diabetic complications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.