Mouse monoclonal antibodies raised to the T-cell line HSB-2 and T-Cell chronic lymphocytic leukemia (T-CLL) cells react with normal human T and B lymphocytes and monocytes
US5158885A · kind A · utility
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4Claims
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Key dates
| Filing date | May 23, 1990 |
| Grant date | Oct 27, 1992 |
| Priority date | — |
| Expiry date | May 23, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The prevent invention relates to two monoclonal antibodies which are broadly reactive with all normal human peripheral blood T and B lymphocytes and monocytes and to hybridoma cell lines which produce these monoclonal antibodies. These monoclonal antibodies are designated WM-66 and WM-63 and the respective hybridoma cell lines are designated F56-2D7 (ECAC 88101104) and F56-4D6 (ECACC 88101103). Both of these monoclonal antibodies react with a previously unrecognized human leucocyte differentiation antigen. The relative molecular mass of the antigen recognized by WM-66 is approximately 65 kilodaltons.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.