Method for flow field flow fractionation
US5160625A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 6, 1991 |
| Grant date | Nov 3, 1992 |
| Priority date | — |
| Expiry date | Dec 6, 2011 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D2313/243
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
An apparatus for flow field flow (FFF) fractionation comprises: a porous hollow fiber (1) which extends longitudinally between end-fittings (2, 3) of a tube (4), one end of said fiber (1) being connected to a first pump (5) for pumping a first carrier liquid into said fiber (1) via a valve (9) for introducing a liquid sample to be fractionated, the other end of said fiber (1) being connected to a container for a second carrier liquid via a flow-through detector (11), for detecting fractions of said sample; a second pump (12) which is connected to the interspace between the tube (4) and the fiber (1) to pump out carrier fluid through the porous fiber wall; and a control unit (6) which is adapted to control said first pump (5) to have a flower flow rate than said second pump (12) during injection and relaxation of the sample, and a higher flow rate than said second pump (12) to elute the sample; and a method for FFF fractionation in a hollow fiber utilizing the steps of sample application, relaxation, flow restoration, and elution whereby the radial flow out of the fiber is controlled by a separate pump.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.