Neisseria-specific DNA probe

US5162199A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Anne Stern · Penzberg, DE
• Karin Wolff · Germering, DE

Key dates

• Filing date: May 31, 1990
• Grant date: Nov 10, 1992
• Expiry date: May 31, 2010

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S435/871
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A Neisseria-specific DNA probe is chosen from the group of the oligonucleotides Opa 1, Opa 2, Opa 3, P III, Pil 1, IgA 1 and IgA 2 or from sequences complementary to these and it can have up to 5 further nucleotides at the 5' and/or 3' end. The probe is suitable for the detection of at least one of the pathogenic Neisseria species N. gonorrhoeae and N. meningitidis under hybridization conditions by the detection of the hybrid formation.