Valproic and (E)-2-valproenoic acid derivatives, and pharmaceutical compositions therefrom
US5162573A · kind A · utility
13Cited by
2References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 17, 1987 |
| Grant date | Nov 10, 1992 |
| Priority date | — |
| Expiry date | Jun 17, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D317/40
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
2-Propyl-2-pentanoic acid (valproic acid) esters and (E)-2-propyl-2-pentenoic acid [(E)-2-valproenoic acid] esters surprisingly proved to have valuable properties, in that they show anticonvulsive and antiepileptic activities comparable with those of valproic acid, as well as an improved bioavailability and a markedly reduced toxicity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.