Patent · US Expired

Method for determining activity of retroviral protease

US5164300A · kind A · utility

15Cited by
1References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 11, 1990
Grant dateNov 17, 1992
Priority date
Expiry dateDec 11, 2010

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S436/815
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Novel fluorogenic substrates for retroviral protease, e.g. HIV protease, having the chemical structure X-Thr-Ile-Nle-Phe(Y)-Gln-Arg-NH.sub.2 wherein X is a fluorogenic group and Y is an acceptor for the fluorogenic group, and their use in a fluorometric method for the determination of retroviral protease is disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.