Preparation of aminocyclopentane acids
US5164503A · kind A · utility
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18Claims
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Key dates
| Filing date | May 13, 1991 |
| Grant date | Nov 17, 1992 |
| Priority date | — |
| Expiry date | May 13, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D311/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process is described for the preparation of compounds of the formula ##STR1## in which W is C.sub.1-7 alkylene PA0 X is cis or trans --CH.dbd.CH-- or --CH.sub.2 Ch.sub.2 -- PA0 Y is a saturated heterocyclic amino group, and PA0 R.sup.2 is substituted or unsubstituted phenyl-, thienyl- or naphthyl-alkyl, or cinnamyl, PA0 and their salts and solvates. The process comprises hydrolysing a corresponding ester, amide, nitrile or ortho-ester. The starting materials are preferably prepared by reducing the corresponding cyclopentanone and hydrolysis can take place simultaneously with reduction.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.