Synergistic tumor therapy with combinations of biologically active anti-tumor antibodies and chemotherapy
US5165922A · kind A · utility
24Cited by
1References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 22, 1990 |
| Grant date | Nov 24, 1992 |
| Priority date | — |
| Expiry date | May 22, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the use of combinations of antibody therapy and chemotherapy in the treatment of malignant disease. More particularly, the invention relates to novel methods of treating patients who have malignant disease and who have shown an unresponsiveness to treatment with standard chemotherapy regimens by administering to those patients (i) an antibody that binds to the malignant cells of the patient and (ii) a chemotherapeutic agent. According to particular embodiments of the invention, anti-glycolipid antibodies are administered to patients who are subsequently treated with standard chemotherapy regimens.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.