Method for inhibing adhesion of white blood cells to endothelial cells
US5166133A · kind A · utility
58Cited by
1References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 14, 1991 |
| Grant date | Nov 24, 1992 |
| Priority date | — |
| Expiry date | May 14, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/8114
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Proteins are described that affect adhesion of white blood cells (WBCs) to endothelial cells (ECs). The proteins include inter-.alpha.-trypsin inhibitor, .alpha..sub.1 -M, and HI-30. When administered in therapeutically effective amounts, these proteins can alter adhesion between WBCs and ECs to ultimately prevent inflammatory-type diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.