Patent · US Expired

11.beta.-aryl-16.alpha.,17.alpha.-cyclohexano-estra-4,9-dienes

US5166199A · kind A · utility

7Cited by

0References

11Claims

0Family size

Assignee

SCHERING CORPORATION · US

Inventors

Helmut Kasch · Jena, DE
Gudrun Bertram · Jena, DE
Anatoli Kurischko · Jena, DE
Kurt Ponsold · Jena, DE

Key dates

Filing date	Aug 15, 1990
Grant date	Nov 24, 1992
Priority date	—
Expiry date	Aug 15, 2010

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P25/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

11.sym.-Aryl-16.alpha.,17.alpha.-cyclohexano-estra-4,9-dienes of formula ##STR1## wherein R.sup.1 is H or a methyl group; PA0 R.sup.2 is --OCH.sub.3, --SCH.sub.3, --N(CH.sub.3).sub.2, --NHCH.sub.3, --CN, --CHO, --COCH.sub.3 or --CHOHCH.sub.3 ; PA0 X is --CHO, --COCH.sub.3, --CH.sub.2 OH, --CHOHCH.sub.3, --CH.sub.2 CHO--C.sub.1-7 -alkyl, --CH.sub.2 CHO--C.sub.1-7 -alkanoyl, --CH.sub.2 O--C.sub.1-7 -alkyl, --CH.sub.2 O--C.sub.1-7-alkanoyl, --COO--C.sub.1-7 -alkyl, CH.sub.3 CH.sub.2 --, --CH.sub.3, --COOH or --CN; and PA0 Y is .dbd.O, .dbd.NOH, .dbd.NOCH.sub.3 or a cyclic thioketal having 2 or 3 ring atoms are provided, as well as pharmaceutical compositions containing said compounds, methods of use of said compounds, and processes for their production.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.