Method for enhancing the systemic delivery of dextromethorphan for the treatment of neurological disorders
US5166207A · kind A · utility
162Cited by
0References
6Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 17, 1991 |
| Grant date | Nov 24, 1992 |
| Priority date | — |
| Expiry date | Jun 17, 2011 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/485
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for enhancing the systemic delivery of dextromethorphan for the treatment of a neurological disorder resulting in injury to nervous tissue, which comprises administering to a patient suffering from the disorder an amount of a cytochrome P450IID6 enzyme inhibitor, sufficient to block dextromethorphan metabolism, and an amount of dextromethorphan sufficient to treat the neurological disorder. Quinidine is particularly suitable for use in the method of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.