Bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
US5166374A · kind A · utility
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1Claims
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Key dates
| Filing date | Sep 18, 1991 |
| Grant date | Nov 24, 1992 |
| Priority date | — |
| Expiry date | Sep 18, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J9/005
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of general formula I ##STR1## wherein R.sub.1 is hydrogen or hydroxy, and the hydroxy group at the 7-position can be either in .alpha. or .beta. configuration, are valuable in human therapy. Compounds I can be prepared by reacting with succinic acid carboanions the corresponding derivatives which have previously been protected, and subsequently deprotecting and decarboxylating them.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.