Preparation of 2,2-disubstituted pentane-1,5-diamines

US5166443A · kind A · utility

Assignee

• BASF SE

Inventors

• Franz Merger · Bischofswerda, DE
• Claus-Ulrich Priester · Ludwigshafen, DE
• Tom Witzel · Ludwigshafen, DE
• Gerhard Koppenhoefer · Ludwigshafen, DE
• Ludwig Schuster · Schifferstadt, DE

Key dates

• Filing date: Mar 17, 1991
• Grant date: Nov 24, 1992
• Expiry date: Mar 17, 2011

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C211/09
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the preparation of a 2,2-disubstituted pentane-1,5-diamine of the formula I ##STR1## where R.sup.1 and R.sup.2, independently of one another, are C.sub.1 - to C.sub.10 -alkyl or C.sub.2 - to C.sub.10 -alkenyl or together are a C.sub.4 - to C.sub.7 -alkylene chain which is unsubstituted or monosubstituted to pentasubstituted by C.sub.1 - to C.sub.4 -alkyl, from a 2,2-disubstituted 4-cyanobutanal of the formula II ##STR2## where R.sup.1 and R.sup.2 are as defined above, comprises, in two spatially separate reaction spaces, PA1 a) reacting the 4-cyanobutanal of the formula II, in a first reaction space, with excess ammonia on an acidic heterogeneous catalyst at from 20.degree. to 150.degree. C. and at from 15 to 500 bar, and PA1 b) hydrogenating the resultant reaction product, in a second reaction space, using excess hydrogen in the presence of excess ammonia on a catalyst containing cobalt, nickel, ruthenium and/or another noble metal, if desired with a basic component or on a basic or neutral carrier, at from 60.degree. to 150.degree. C. and at from 50 to 500 bar.