Article comprising a dispensing container that includes solid polymeric material in contact with an antiplaque oral composition with which it is compatible
US5167951A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 6, 1990 |
| Grant date | Dec 1, 1992 |
| Priority date | — |
| Expiry date | Apr 6, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/87
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An oral composition, such as a paste or gel dentifrice or a liquid mouthwash, containing a substantially water insoluble non-cationic antibacterial agent, such as triclosan, which, when used to clean the teeth or rinse the mouth, acts to decrease plaque on the teeth, is packaged in a dispensing container which includes a solid polymeric material, such as polyfluoroethylene, which is compatible with the antibacterial agent so that excessive loss of anti-plaque activity of such agent on storage is avoided. Alternatively, various other polymers may be employed as container parts, which normally would cause excessive losses of anti-plaque action of the antibacterial agent in the composition, but such action is countered by the presence of a stabilizer, such as a terpene, e.g., limonene, in the oral composition formula. The oral composition preferably contains a tooth hardening proportion of a source of fluoride ions, an anti-tartar proportion of a polyphosphate, a stabilizing proportion (in conjunction with the fluoride source) for the polyphosphate, of a polyvinyl methyl ether-maleic anhydride copolymer, and normal adjuvants for the oral preparation. A method for inhibiting developmen…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.