Hirudin-coated biocompatible substance
US5167960A · kind A · utility
81Cited by
14References
35Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 3, 1988 |
| Grant date | Dec 1, 1992 |
| Priority date | — |
| Expiry date | Aug 3, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L33/0029
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Disclosed is a biocompatible, thromboresistant substance useful for implantable and extracorpeoreal devices in contact with the vascular system, and methods for producing the same. The biocompatible, thromboresistant substance comprises a synthetic, biocompatible material, at least one biocompatible base coat layer adhered to at least one surface of the material, and a thrombogenesis inhibitor immobilized on the base coat layer via a component capable of binding the inhibitor. The thrombogenesis inhibitor is hirudin, or an active analog or fragment thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.