Patent · US Expired

Ion-permeable polymer joint for use in capillary electrophoresis

US5169510A · kind A · utility

11Cited by
2References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 2, 1992
Grant dateDec 8, 1992
Priority date
Expiry dateMar 2, 2012

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N27/4473
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Improved capillary electrophoresis (CE) apparatus (10) is provided which includes an intermediate grounding joint (34) serving to isolate delicate electrochemical detectors (32, 54, 58) from the high voltage CE power supply (20). The joint (34) includes a fracture (36) close to the detection end (22) of the apparatus (10) which is covered by a Nafion sleeve (38). The joint (34) is immersed in an ionic buffer reservoir (46) which includes a grounded cathode (48). In fabrication procedures, a capillary tube (12) is scored in proximity to one end (22) thereof, and the Nafion sleeve (38) is slid over the score line. The sleeve (38) is then sealed with epoxy (40, 42) at the ends thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.