Ion-permeable polymer joint for use in capillary electrophoresis
US5169510A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 2, 1992 |
| Grant date | Dec 8, 1992 |
| Priority date | — |
| Expiry date | Mar 2, 2012 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N27/4473
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Improved capillary electrophoresis (CE) apparatus (10) is provided which includes an intermediate grounding joint (34) serving to isolate delicate electrochemical detectors (32, 54, 58) from the high voltage CE power supply (20). The joint (34) includes a fracture (36) close to the detection end (22) of the apparatus (10) which is covered by a Nafion sleeve (38). The joint (34) is immersed in an ionic buffer reservoir (46) which includes a grounded cathode (48). In fabrication procedures, a capillary tube (12) is scored in proximity to one end (22) thereof, and the Nafion sleeve (38) is slid over the score line. The sleeve (38) is then sealed with epoxy (40, 42) at the ends thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.