Biodegradable particle coatings having a protein covalently immobilized by means of a crosslinking agent and processes for making same
US5169754A · kind A · utility
57Cited by
15References
48Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 31, 1990 |
| Grant date | Dec 8, 1992 |
| Priority date | — |
| Expiry date | Oct 31, 2010 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2998
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates generally to colloidal particles having a crosslinked coating with pendent functional groups attached thereto. Magnetic and non-magnetic particles have a biodegradable, crosslinked gelatin coating to which is covalently attached pendent biological substances or molecules, especially monoclonal antibodies. The monoclonal antibodies so attached are useful in a variety of positive and negative biological assays.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.