Removal of riboflavin from fermentation suspensions

US5169759A · kind A · utility

Assignee

• BASF SE

Inventors

• Tillmann Faust · Bad Dürkheim, DE
• Joachim Meyer · Frankenthal (Pfalz), DE
• Georg Wellinghoff · Mannheim, DE
• Walter Gosele · Heidelberg, DE
• Christoph Martin · Dietzenbach, DE
• Johannes Grimmer · Aarhus, DK

Key dates

• Filing date: Jan 23, 1991
• Grant date: Dec 8, 1992
• Expiry date: Jan 23, 2011

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P25/00
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Riboflavin is removed from fermentation suspensions by them being heated at from 50.degree. to 90.degree. C. for from 1 to 3 hours, than cooled to from 0.degree. to 30.degree. C. over a period of from 1 to 5 hours, and subsequently being centrifuged to give a sediment fraction and liquid fraction in such a way that the sediment fraction contains predominantly riboflavin crystals as solid, and the liquid fraction contains virtually no crystalline riboflavin, and, where appropriate, resuspending the sediment fraction in from 0.5 to 2 parts by volume of water per part by volume of sediment fraction and repeating procedure c.