Method of suppressing appetite by administration of tetrahydro-beta-carboline derivatives
US5169852A · kind A · utility
10Cited by
2References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 14, 1990 |
| Grant date | Dec 8, 1992 |
| Priority date | — |
| Expiry date | Dec 14, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/44
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of formula I are useful for suppressing appetite, and for altering macronutrient preferences, ##STR1## where the R.sub.2 -R.sub.9 substituents are so selected as to meet a defined quantitative structure activity relationship (QSAR) quantity relating to the partition coefficient of the compound, the net charge on the ring nitrogen, and the radical superfdelocalizability at the position-8 ring carbon.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.