Thiazolidinone derivatives, pharmaceutical compositions containing them and process for preparing same
US5169859A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 18, 1991 |
| Grant date | Dec 8, 1992 |
| Priority date | — |
| Expiry date | Jul 18, 2011 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P1/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to novel compounds of the general formula (I) ##STR1## wherein R means hydrogen or C.sub.1-4 alkyl group; and PA0 Y stands for cyano, trifluoromethyl, aryloxy or aryl(C.sub.1-4 alkyl)oxy group. The compounds according to the invention show a gastric acid secretion-inhibiting effect and therefore, they are useful for the treatment of gastric and duodenal ulcers. In addition, they exert a cytoprotective action against gastric laesions induced, e.g. by indomethacin or acid-containing alcohol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.