Patent · US Expired

Thiazolidinone derivatives, pharmaceutical compositions containing them and process for preparing same

US5169859A · kind A · utility

0Cited by
1References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 18, 1991
Grant dateDec 8, 1992
Priority date
Expiry dateJul 18, 2011

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P1/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to novel compounds of the general formula (I) ##STR1## wherein R means hydrogen or C.sub.1-4 alkyl group; and PA0 Y stands for cyano, trifluoromethyl, aryloxy or aryl(C.sub.1-4 alkyl)oxy group. The compounds according to the invention show a gastric acid secretion-inhibiting effect and therefore, they are useful for the treatment of gastric and duodenal ulcers. In addition, they exert a cytoprotective action against gastric laesions induced, e.g. by indomethacin or acid-containing alcohol.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.