Treated corneal prosthetic device
US5171318A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 21, 1992 |
| Grant date | Dec 15, 1992 |
| Priority date | — |
| Expiry date | Jan 21, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2300/606
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Prosthetic devices are prepared for subepithelial implantation by coating their surfaces with a coating comprising crosslinked or uncrosslinked fibronectin. If the surface of the device comprises a material which does not normally bind fibronectin, it is pretreated, for example, by coating with poly(L-lysine). The coated prosthetic device is implanted by removing a portion of the epithelium, affixing the coated device to the subepithelial tissue optionally replacing all or part of the removed epithelium, and allowing new epithelial tissue to grow over and affix itself to the surface of the prosthetic device. The method of the invention can be used to implant contact lenses permanently beneath the epithelium of the cornea.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.