Monoclonal antibodies reactive with a cell-surface gylcoprotein expressed on human carcinomas
US5171666A · kind A · utility
7Cited by
9References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 19, 1988 |
| Grant date | Dec 15, 1992 |
| Priority date | — |
| Expiry date | Oct 19, 2008 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/864
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to a novel tumor-associated antigen that is a cell-surface glycoprotein having a molecular weight in the range of 110,000-140,000 daltons that is present in a variety of carcinomas, including squamous cell carcinomas and adenocarcinomas. The invention also comprises antibodies reactive with the antigen, hybridoma cell lines that produce the antibodies of the invention, and methods for using the antibodies in the diagnosis and treatment of cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.