Lipopolyamines, their preparation and their use
US5171678A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 17, 1990 |
| Grant date | Dec 15, 1992 |
| Priority date | — |
| Expiry date | Apr 17, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
New lipopolyamines of general formula (I), their salts, their preparation and their use. ##STR1## n=1 to 5 and m=2 to 6; R represents a radical ##STR2## (R.sub.1 and R.sub.2 : aliphatic radical containing 12 to 22 carbon atoms; R: hydrogen atom or alkyl radical optionally substituted with phenyl), or a radical ##STR3## (X=CH.sub.2, CO; R.sub.3 and R.sub.4 aliphatic radical containing 11 to 21 carbon atoms), their preparation and their use. The lipopolyamines of general formula (I) are especially useful as vectors for the transfection of eukaryotic cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.