Self-corrected assay device
US5171688A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 23, 1989 |
| Grant date | Dec 15, 1992 |
| Priority date | — |
| Expiry date | Aug 23, 2009 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/104165
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An assay device and method for determining the concentration of an analyte in a fluid sample. The device includes a porous-matrix reservoir which receives the sample to be assayed, and at least two reaction zones into which sample fluid is drawn from the reservoir. In an embodiment containing two reaction zones, a single-point standard curve which corrects for reduced-signal effects related to loss of reagent activity and linear inhibition effects, is used to determine analyte concentration. In an embodiment containing three reaction zones, a two-point standard curve which corrects for reduced-signal effects related loss of reagent activity and non-linear inhibition effects, is used to determine analyte concentration. Also disclosed is an apparatus which uses the device for automated or semi-automated analyte assay.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.